反应详情

In 20 ml methyl cellosolve was heated 2.0 g (0.0054 mol) of 2-chloro-5-(2-chloro-4-trifluoromethylphenoxy)benzoyl chloride to temperatures of 80°-120° C. for 3 hours with stirring. After methyl cellosolve was distilled off, the residue was extracted with benzene. The extract was washed with a dilute aqueous solution of caustic soda and with water, and then dehydrated by adding sodium sulfate. By vacuum concentration thereof 2.2 g (0.0047 mol) of the intended product was obtained as a viscous oily substance; yield 87.0%, nD25 1.5321.

1. distillationAfter methyl cellosolve was distilled off
2. extractionthe residue was extracted with benzene
3. washThe extract was washed with a dilute aqueous solution of caustic soda and with water
4. additionby adding sodium sulfate
5. concentrationBy vacuum concentration