Water → Ethoxyethoxyethoxyethyl-2-chloro-5-(2-chloro-4-trifluoromethylphenoxy)benzoate

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Reaction Steps

In 20 ml pyridine was dissolved 2.0 g (0.0167 mol) of triethylene glycol monoethyl ether, and while stirring at room temperature, 1.8 g (0.0049 mol) of 2-chloro-5-(2-chloro-4-trifluoromethylphenoxy)benzoyl chloride was added. After 4-hour stirring, the reaction fluid was poured into 200 ml of water, and extracted with benzene. The extract was washed with a dilute aqueous solution of caustic soda and then with dilute hydrochloric acid. By concentration 1.4 g (0.0031 mol) of the intended product was obtained as a viscous oily substance, yield 63.3%, nD28 1.5175.

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