1,4-Dioxane → HCID 20535634, compound

Participants

Reaction Steps

To a solution of ethyl 5-(2-iodopropoxy)-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylate (0.1 g) in 50% aqueous dioxan (15 ml) was added silver perchlorate (0.08 g). The solution was heated at reflux for 4 hours, filtered and evaporated to dryness. The brown, solid residue was crystallised from ethanol giving ethyl 5-(2-hydroxypropoxy)-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylate identical in all respects with authentic material.

Provenance & Evidence