N-bromobutanimide → HCID 20535634, compound

Participants

Reaction Steps

A mixture of ethyl 2,3-dihydro-5-(2-hydroxypropoxy)-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylate and N-bromosuccinimide (1.1 g) was heated at reflux in carbon tetrachloride (100 ml) for 6 hours. The solution was cooled, washed with water, dried and evaporated. The solid residue was crystallised from ethanol giving ethyl 5-(2-hydroxypropoxy)-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylate identical in all respects with authentic material.

Provenance & Evidence