反应详情

A mixture of 5.0 g (0.014 mole) of ethyl (E)-3-[5-(1-oxododecyl)-2-furanyl]-2-propenoate and 108 ml of ethanol, is heated to reflux. To the mixture is added 50 ml of 1 N aqueous sodium hydroxide, the ethanol is distilled off being replaced with water, and the aqueous solution is cooled to room temperature acidified with 200 ml of 1 N hydrochloric acid. The solid is collected by filtration and dried. Recrystallization from methanol gives (E)-3-[5-(1-oxododecyl)-2-furanyl]-2-propenoic acid, mp 122°-127° C.

1. temperatureis heated to reflux
2. distillationthe ethanol is distilled off
3. filtrationThe solid is collected by filtration
4. customdried
5. customRecrystallization from methanol