反应详情

By following the same procedure as in Example 49 using a mixture of 240 mg. of 2-carboxymethylbenzoic acid, 300 mg. of 2-amino-2-methylpropanethiol, 164 mg. of sodium acetate, and 5 ml. of o-dichlorobenzene, 120 mg. of 3,3-dimethyl-5-oxo-2,3-dihydro-5H-thiazolo[3,2-b]isoquinoline was obtained.

1. additiona mixture of 240 mg