Acetone → 2-[(N-methyl-N-n-octadecylamino)methyl]-2-propenenitrile propionic acid salt

HRID 1156372Notes

Reaction equation

HRID 1156372 reaction equation
[CH3:1][N:2]([CH2:21][C:22](=[CH2:25])[C:23]#[N:24])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].CC(C)=O.[C:30]([OH:34])(=[O:33])[CH2:31][CH3:32]>CCOCC>[C:30]([OH:34])(=[O:33])[CH2:31][CH3:32].[CH3:1][N:2]([CH2:21][C:22](=[CH2:25])[C:23]#[N:24])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

Participants

5

Reactant 3

HCID 180AcetoneHCID 1032Propionic AcidHCID 128514082-[(N-Methyl-N-n-octadecylamino)methyl]-2-propenenitrile

Product 1

HCID 205359852-[(N-methyl-N-n-octadecylamino)methyl]-2-propenenitrile propionic acid salt

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 2[(N-methyl-N-n-octadecylamino)methyl]-2-propenenitrile (1.7 g., 0.005 mole) in 10 ml. of acetone is mixed with propionic acid (0.41 g., 0.0055 mole). The solvent is stripped in vacuo, and the residue is dissolved in a small volume of ether. Low boiling petroleum ether is gradually added until the ice cold solution became turbid. After standing at 10° C. for 12 hours the product is removed by suction filtrations and then washed with cold petroleum ether followed by drying at ambient temperature.

Workup

  1. customthe product is removed by suction filtrations
  2. washwashed with cold petroleum ether
  3. customby drying at ambient temperature

Sources & evidence

ORD record
ord-88114c9c2e7e4fc3b09c64c79c8cd2f3
Source dataset
uspto-grants-1982_06
Patent number
US04335141

Reaction notes

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