Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 4(2H)-Benzofuranone, 2-ethoxy-3,5,6,7-tetrahydro- | HCID 11063039 | — |
| Product | 1,5,6,7-Tetrahydro-4H-indol-4-one | HCID 280229 | 54% |
Reaction Steps
96.5 mg of 2-ethoxy-4-oxo-2,3,4,5,6,7-hexahydrocoumarone and 1.5 ml of 28% aqueous ammonia were admixed in a glass tube which was sealed and heated at 100° C. for 14 hours. The reaction mixture was treated in the same manner as Example 11 to give 38.4 mg of 4-oxo-4,5,6,7-tetrahydroindole (yield 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04336202 |
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| Source dataset | uspto-grants-1982_06 |
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| ORD ID | ord-116ca53683b0484f8e251164ad5c75b5 |
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| Source note | uspto-grants-1982_06 |
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