反应详情

A mixture of 1.7 g (0.01 m) of 4,6-diamino-2-guanidinopyrimidine prepared as in Example 2, 0.9 g (0.01 m) of S-methylisothiourea and 150 ml of methanol is heated at reflux overnight. Evaporation of the volatiles gives 6-amino-2,4-diguanidinopyrimidine.

1. temperatureis heated
2. temperatureat reflux overnight
3. customEvaporation of the volatiles