2-Methyl-2-thiopseudourea → HCID 178512589, compound

HRID 1156511Notes

Reaction equation

HRID 1156511 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH:9][C:10]([NH2:12])=[NH:11])[N:3]=1.CS[C:15](=[NH:17])[NH2:16]>CO>[NH2:8][C:6]1[N:5]=[C:4]([NH:9][C:10]([NH2:12])=[NH:11])[N:3]=[C:2]([NH:1][C:15]([NH2:17])=[NH:16])[CH:7]=1

Participants

4

Reactant 2

HCID 51422-Methyl-2-thiopseudoureaHCID 178512731HCID 178512731, compound

Product 1

HCID 178512589HCID 178512589, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 1.7 g (0.01 m) of 4,6-diamino-2-guanidinopyrimidine prepared as in Example 2, 0.9 g (0.01 m) of S-methylisothiourea and 150 ml of methanol is heated at reflux overnight. Evaporation of the volatiles gives 6-amino-2,4-diguanidinopyrimidine.

Workup

  1. temperatureis heated
  2. temperatureat reflux overnight
  3. customEvaporation of the volatiles

Sources & evidence

ORD record
ord-3e4267fd2d06419bb9c7259a17cb77fe
Source dataset
uspto-grants-1982_06
Patent number
US04336254

Reaction notes

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