Potassium Hydroxide → HCID 13037784, compound

Participants

Reaction Steps

In 20 ml of ethanol and 2.4 ml of dioxane there was suspended 1.15 g (4 mMol) of the ester product prepared in Step B above. There was then added 3 ml of 2 N potassium hydroxide, whereupon a precipitate formed. The reaction mixture was stirred overnight at room temperature. The mixture was evaporated to dryness, an then water was added, whereupon most of the solid dissolved. The mixture was then made acidic to pH 1.0 using 6 N hydrochloric acid. A white solid was obtained which was filtered off, washed with water and dried. The solid was crystallized from benzene to give product, m.p. 140°-142° C. Analysis:

Provenance & Evidence