Cyclohexanecarbonyl chloride → HCID 53644797, compound

HRID 1156660Notes

Reaction equation

C1(C(Cl)=O)CCCCCC1.C1(C(Cl)=O)CCCCC1.[C:20]([NH:24][CH2:25][C:26]([C:28]1[CH:33]=[CH:32][C:31]([O:34][C:35]([CH:37]2[CH2:43][CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]2)=[O:36])=[C:30]([O:44][C:45]([CH:47]2[CH2:53][CH2:52][CH2:51][CH2:50][CH2:49][CH2:48]2)=[O:46])[CH:29]=1)=[O:27])([CH3:23])([CH3:22])[CH3:21]>>[CH:47]1([C:45]([O:44][C:30]2[CH:29]=[C:28]([CH:33]=[CH:32][C:31]=2[O:34][C:35]([CH:37]2[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]2)=[O:36])[CH:26]([OH:27])[CH2:25][NH:24][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:46])[CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53]1

Participants

Reactant 3

HCID 75938Cyclohexanecarbonyl chloride

HCID 12556870Cycloheptanecarbonyl chloride

HCID 20535439HCID 20535439, compound

Product 1

HCID 53644797HCID 53644797, compound

Procedure

When cycloheptanecarbonyl chloride is substituted for the cyclohexanecarbonyl chloride in the procedure described in Example 15A above, the acylation product obtained is 3,4-bis(cycloheptanecarbonyloxy)phenyl tert-butylaminomethyl ketone; and when this product is catalytically hydrogenated using the procedure described in Example 15B above, there is obtained 3,4-bis(cycloheptanecarbonyloxy)-alpha-(tert-butylaminomethyl)benzyl alcohol.

Workup

customobtained

Sources & evidence

ORD record: ord-67637abe02ff4429a962449d8380e5c0
Source dataset: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04336400

Reaction notes

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