反应详情

温度

115 °C

Into a 2 liter reaction vessel equipped with stirrer, thermometer, heating mantle and overhead condenser with azeotrope takeoff apparatus is placed 488 grams of beta-phenylethyl alcohol; 440 grams of cyclohexanol and 100 grams of concentrated sulfuric acid. The reaction mass is then heated to a temperature of 115° C. and maintained at a temperature in the range of 104°-127° C. at reflux while azeotropically removing 80 ml water, for a period of 3 hours. At the end of the 3 hour period, a sample is analyzed by means of GLC analysis (conditions: 180° C. isothermal using an SE-30 packed column). FIG. 1A is the GLC profile of the reaction product at this point.

1. customInto a 2 liter reaction vessel
2. customequipped with stirrer
3. temperaturethermometer, heating mantle and overhead condenser with azeotrope takeoff apparatus
4. temperaturemaintained at a temperature in the range of 104°-127° C.
5. temperatureat reflux
6. customwhile azeotropically removing 80 ml water
7. customAt the end of the 3 hour period
8. custom180° C.