HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 1-(p-Methoxyphenyl)-4-morpholino-1-buten-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Reactant | 1-(4-Morpholinyl)acetone | HCID 11029948 | — |
| Product | 1-(p-Methoxyphenyl)-4-morpholino-1-buten-3-one | HCID 54451066 | 72% |
Reaction Steps
Condensation 13.6 g (0.1 mole) of p-methoxybenzaldehyde is dissolved in 14.3 g (0.1 mole) of morpholinoacetone and this solution is added dropwise to 100 cm3 of a solution of 1 N sodium hydroxide cooled in an ice-containing water bath. The temperature is allowed to return to ambient temperature while stirring for 5 hours. The precipitate obtained is filtered and rinsed several times with water. 18.8 g of 1-(p-methoxyphenyl)-4-morpholino-1-buten-3-one is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337252 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-02709f6585a74823a86feb769a346555 |
| Source note | uspto-grants-1982_06 |