HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propynenitrile → 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propynenitrile | HCID 14055 | — |
| Reactant | (3Z)-3-diazo-1H-indol-2-one | HCID 136455454 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carbonitrile | HCID 135735621 | — |
Reaction Steps
6.0 g (0.04 mole) of 3-diazooxindole and 2.2 g (0.045 mole) of cyanoacetylene are taken up in benzene (250 ml) and refluxed overnight under N2. The mixture is cooled and the beige-colored precipitates are filtered off. The crude product is dried in a vacuum oven at room temperature for 3 hours. Yield: 5.2 g, m.p. 302°-304°. Percent yield: 65.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337255 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-c2999f7cabeb43a0ad198f2bdab2d119 |
| Source note | uspto-grants-1982_06 |