Acetyl chloride → HCID 20469688, compound

HRID 1156780Notes

Reaction equation

N1(CCO)CCNCC1.[C:10]([N:13]1[CH2:18][CH2:17][N:16]([CH2:19][CH2:20][OH:21])[CH2:15][CH2:14]1)(=[O:12])[CH3:11].C(Cl)(=O)C.[CH3:26][S:27](Cl)(=[O:29])=[O:28]>>[S:27]([O:21][CH2:20][CH2:19][N:16]1[CH2:17][CH2:18][N:13]([C:10](=[O:12])[CH3:11])[CH2:14][CH2:15]1)(=[O:29])(=[O:28])[CH3:26]

Participants

Reactant 4

HCID 6367Acetyl chloride

HCID 76771-(2-Hydroxyethyl)piperazine

HCID 31297Methanesulfonyl chloride

HCID 47396291-Acetyl-4-(2-hydroxyethyl)piperazine

Product 1

HCID 20469688HCID 20469688, compound

Procedure

In the same process, 2-piperazinoethanol is replaced by equivalent 2-(4-acetylpiperazino)ethanol and acetyl chloride is replaced by equivalent methanesulfonyl chloride to produce 2-(4-acetylpiperazino)ethyl mesylate.

Sources & evidence

ORD record: ord-ae1c4bbe1ba94a94b0396c88aea933fb
Source dataset: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04337250

Reaction notes

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