反应详情

Thirty-four (34) grams of 1-(4-bromophenyl)-5-methyl-3,4-dihydroisoquinoline was reacted for 8 hours together with 200 g of active manganese dioxide and 1000 ml of benzene. After the reaction, the manganese dioxide was removed by filtration, and the benzene was distilled off. Recrystallization of the resulting colorless crystals (29 g) from cyclohexane afforded 1-(4-bromophenyl)-5-methylisoquinoline as colorless needles having a melting point of 126.5° to 127.5° C.

1. customAfter the reaction
2. customthe manganese dioxide was removed by filtration
3. distillationthe benzene was distilled off
4. customRecrystallization of the resulting colorless crystals (29 g) from cyclohexane