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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1156876Generated: October 30, 2026

Diphenyl disulfide → 1-(4-Fluorophenyl)-5-methylisoquinoline

https://huagongshe.com/reaction/1156876

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenyl disulfideHCID 13436—
Reactant1-(4-Fluorophenyl)-5-methyl-3,4-dihydroisoquinolineHCID 12851822—
Product1-(4-Fluorophenyl)-5-methylisoquinolineHCID 12851835—

Reaction Steps

Diphenyl disulfide was reacted with 1-(4-fluorophenyl)-5-methyl-3,4-dihydroisoquinoline in the same way as in step (c) of Example 1 to afford 1-(4-fluorophenyl)-5-methylisoquinoline as colorless needles having a melting point of 91° to 92° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04337256
Source datasetuspto-grants-1982_06
ORD IDord-e84c131ded2844009499b2f176ab999e
Source noteuspto-grants-1982_06