Methanol → HCID 12851814, compound

Participants

Reaction Steps

1-(4-Nitrobenzoyl)amino-2-[2-(4-nitrobenzoyloxymethyl)phenyl]ethane (24 g) was added to a solution of 300 ml of methanol, 2.6 g of sodium hydroxide and 100 ml of water. The mixture was refluxed for 1 hour. After the reaction, the solvent was distilled off, and water was added. The crystals that precipitated were collected by filtration, washed with water, and recrystallized from ethanol-n-hexane to afford 14.8 g of 1-(4-nitrobenzoyl)amino-2-(2-hydroxymethylphenyl)ethane having a melting point of 137.3° to 137.6° C.

Provenance & Evidence