Cyclohexanecarbonyl chloride → 1-Cyclohexylcarbonylamino-2-(2-chlorophenyl)ethane

HRID 1156914Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[Cl:10].[CH:11]1([C:17](Cl)=[O:18])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1>>[CH:11]1([C:17]([NH:1][CH2:2][CH2:3][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[Cl:10])=[O:18])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

Reactant 2

HCID 75938Cyclohexanecarbonyl chloride

HCID 831172-(2-Chlorophenyl)ethylamine

Product 1

HCID 128518191-Cyclohexylcarbonylamino-2-(2-chlorophenyl)ethane

Procedure

1-Amino-2-(2-chlorophenyl)ethane and cyclohexanecarbonyl chloride was reacted in the same way as in step (a) of Example 13 to afford 1-cyclohexylcarbonylamino-2-(2-chlorophenyl)ethane having a melting point of 93.5° to 93.9° C.

Sources & evidence

ORD record: ord-a58771ec449648f5956368425f2ede2f
Source dataset: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04337256

Reaction notes

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