Diphenyl disulfide → 1-Cyclohexyl-5-chloroisoquinoline

HRID 1156916Notes

Reaction equation

HRID 1156916 reaction equation
[CH:1]1([C:7]2[C:16]3[C:11](=[C:12]([Cl:17])[CH:13]=[CH:14][CH:15]=3)[CH2:10][CH2:9][N:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C1(SSC2C=CC=CC=2)C=CC=CC=1>>[CH:1]1([C:7]2[C:16]3[C:11](=[C:12]([Cl:17])[CH:13]=[CH:14][CH:15]=3)[CH:10]=[CH:9][N:8]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 13436Diphenyl disulfideHCID 205338811-Cyclohexyl-5-chloro-3,4-dihydroisoquinoline

Product 1

HCID 205338961-Cyclohexyl-5-chloroisoquinoline

Procedure

1-Cyclohexyl-5-chloro-3,4-dihydroisoquinoline and diphenyl disulfide were reacted in the same way as in step (c) of Example 13 to afford 1-cyclohexyl-5-chloroisoquinoline as an oil.

Sources & evidence

ORD record
ord-99f10bf41ffa4620b71a9ad37cd5a61a
Source dataset
uspto-grants-1982_06
Patent number
US04337256

Reaction notes

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