Sodium Cyanide → HCID 12832774, compound

HRID 1156919Notes

Reaction equation

HRID 1156919 reaction equation
[CH:1]1([C:7]2[C:16]3[C:11](=[C:12]([CH2:17]Cl)[CH:13]=[CH:14][CH:15]=3)[CH:10]=[CH:9][N:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C-:19]#[N:20].[Na+]>>[CH:1]1([C:7]2[C:16]3[CH:15]=[CH:14][CH:13]=[C:12]([CH2:17][C:19]#[N:20])[C:11]=3[CH:10]=[CH:9][N:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 8929Sodium CyanideHCID 12851852HCID 12851852, compound

Product 1

HCID 12832774HCID 12832774, compound

Procedure

1-Cyclohexyl-5-chloromethylisoquinoline and sodium cyanide were reacted in the same way as in step (h) of Example 13 to afford 1-cyclohexylisoquinoline-5-acetonitrile having a melting point of 85.3° to 85.6° C.

Sources & evidence

ORD record
ord-35328530426a4d4e91c8321b2ad44363
Source dataset
uspto-grants-1982_06
Patent number
US04337256

Reaction notes

Loading…