HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isovaleryl chloride → 1-Isovalerylamino-2-(2-hydroxymethylphenyl)ethane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isovaleryl chloride | HCID 66054 | — |
| Reactant | [2-(2-Aminoethyl)phenyl]methanol | HCID 12832783 | — |
| Reactant | 1-Phenyl-5-chloro-3,4-dihydroisoquinoline | HCID 14998911 | — |
| Product | 1-Isovalerylamino-2-(2-hydroxymethylphenyl)ethane | HCID 20533962 | — |
Reaction Steps
1-Amino-2-(2-hydroxymethylphenyl)ethane and isovaleryl chloride were successively reacted in the same way as in steps (b) and (c) of Example 12 to afford 1-isovalerylamino-2-(2-hydroxymethylphenyl)ethane. The product was successively reacted in the same way as in steps (d), (e), (f), and (g) of Example 12 to afford 1-isobutylisoquinoline-5-acetonitrile as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337256 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-5e764897f44d4479ad7d768761b998f3 |
| Source note | uspto-grants-1982_06 |