HCID 12917743, compound → 2-n-Butyl-5-hydroxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole

HRID 1156967Notes

Reaction equation

HRID 1156967 reaction equation
[CH2:1]([C:5]1[S:6][C:7]2[CH2:13][CH2:12][CH:11]([C:14](OCC)=[O:15])[CH2:10][C:8]=2[N:9]=1)[CH2:2][CH2:3][CH3:4]>CCOCC>[CH2:1]([C:5]1[S:6][C:7]2[CH2:13][CH2:12][CH:11]([CH2:14][OH:15])[CH2:10][C:8]=2[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 12917743HCID 12917743, compound

Product 1

HCID 129177552-n-Butyl-5-hydroxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazoleYield 89%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The compound is prepared by reduction of the above derivative (III) with AlLiH4 in ether at room temperature. B.p.0.15 =138°-142° C. Yield: 89%.

Workup

  1. customB.p.0.15 =138°-142° C

Sources & evidence

ORD record
ord-afa98a571b07408e8cf237274eaf45c9
Source dataset
uspto-grants-1982_06
Patent number
US04337343

Reaction notes

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