HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-4-Hydroxymandelic acid → Hydroxyphenylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-4-Hydroxymandelic acid | HCID 328 | — |
| Reactant | Water | HCID 962 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Hydroxyphenylacetic acid | HCID 127 | — |
Reaction Steps
The catalytic reduction was carried out in the same manner as in Example 1 except that the water-containing acetic acid was employed in an amount of 3 times (Example 15) or 8.8 times (Example 16) the weight of 4-hydroxymandelic acid. The yields of 4-hydroxyphenylacetic acid were 78% by mole (Example 15) and 95% by mole (Example 16).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04337355 |
| Source dataset | uspto-grants-1982_06 |
| ORD ID | ord-e19c11098441411f83f4dcd288a7d383 |
| Source note | uspto-grants-1982_06 |