Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromoacetic Acid | HCID 6227 | — |
| Reactant | 2-Amino-3-chlorobenzene-1-thiol | HCID 12678667 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12899263 | HCID 12899263 | 78.3% |
Reaction Steps
The zine salt (2.0 g) of 2-amino-3-chlorothiophenol was suspended in water (30 ml), and bromoacetic acid (1.6 g) was added thereto, followed by stirring at 70° C. for 3 hours. The precipitated crystals were filtered, washed with water and dried to obtain 1.8 g of the objective 5-chloro-2,3-dihydro-1,4-benzothiazine-3-one (m.p. 160°-161° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04337357 |
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| Source dataset | uspto-grants-1982_06 |
|---|
| ORD ID | ord-ef3f4db5c75d41449f00d1cca5cb6e58 |
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| Source note | uspto-grants-1982_06 |
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