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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1157158Generated: November 2, 2026

2-Benzyloxy-5-nitro-biphenyl → 2-Biphenylol, 5-nitro-

https://huagongshe.com/reaction/1157158

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Benzyloxy-5-nitro-biphenylHCID 58985253—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-Biphenylol, 5-nitro-HCID 2027865.4%

Reaction Steps

To a solution of 2-benzyloxy-5-nitro-biphenyl (81 mg, 0.27 mmol)) in 5 mL of methanol was added catalytic amount of 5% palladium on carbon under H2. The mixture was stirred under H2 for 3 hrs and filtered through celite. The filtrate was concentrated to give 2-hydroxy-5-nitro-biphenyl (38 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07807672B2
Source datasetuspto-grants-2010_10
ORD IDord-be467441b133467eb389b365ed88e80a
Source noteuspto-grants-2010_10