HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Piperidin-4-yl-(4-pyrimidin-2-yl-phenyl)-amine, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-(4-Pyrimidin-2-yl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester | HCID 58985153 | — |
| Product | Piperidin-4-yl-(4-pyrimidin-2-yl-phenyl)-amine, hydrochloride | HCID 68423386 | — |
Reaction Steps
Stirred 4-(4-Pyrimidin-2-yl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester (110 mg, 0.310 mmol) in 4M HCl (20 ml) at room temperature for 1 hour. Solvent was evaporated yielding desired product piperidin-4-yl-(4-pyrimidin-2-yl-phenyl)-amine, hydrochloride (114 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807672B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-a069523144e74a46bc0076cc7a5df77f |
| Source note | uspto-grants-2010_10 |