Tetrabutylammonium Fluoride → HCID 59511369, compound

Participants

Reaction Steps

Tetrabutylammonium fluoride (1.8 ml, 1 M in THF) was added to 1-tert-butoxycarbonylmethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-pyrrolidine-3-carboxylic acid ethyl ester (726 mg, 1.8 mmol). The reaction solution was stirred for half hour and purified by column chromatography using solution of ethyl acetate in hexanes (1:1), then ethyl acetate to provide the title product (350 mg, 68%).

Provenance & Evidence