HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoromethanesulfonate → HCID 53983472, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoromethanesulfonate | HCID 2758875 | — |
| Reactant | (S)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoate | HCID 10789275 | — |
| Reactant | methyl (R)-2-tert-butoxy-carbonylamino-3-(4-hydroxyphenyl)propionate | HCID 86601622 | — |
| Product | HCID 53983472 | HCID 53983472 | 91% |
Reaction Steps
In a manner similar to the preparation of ethyl (S)-2-tert-butoxycarbonylamino-3-(4-trifluoromethanesulfonyloxyphenyl)propionate (Example 1b), using 25 g (84.7 mmol) of methyl (R)-2-tert-butoxy-carbonylamino-3-(4-hydroxyphenyl)propionate, 33 g of triflate are isolated with a 91% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807669B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-faab9a4b19ba4088ab3ea3027599d3fc |
| Source note | uspto-grants-2010_10 |