Ammonia → HCID 68643684, compound

HRID 1157687Notes

Reaction equation

HRID 1157687 reaction equation
C[N:2]1[CH:7]=[C:6]([N+]([O-])=O)[CH:5]=[C:4]([N+:11]([O-:13])=[O:12])[C:3]1=O.[CH3:15][N:16]1[CH2:21]CC[C:18](=O)[CH2:17]1.N>CO>[CH3:15][N:16]1[CH2:17][CH2:18][C:6]2[C:7](=[N:2][CH:3]=[C:4]([N+:11]([O-:13])=[O:12])[CH:5]=2)[CH2:21]1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 796563-Piperidinone, 1-methyl-HCID 36212361-Methyl-3,5-dinitro-1H-pyridin-2-one

Product 1

HCID 68643684HCID 68643684, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
60 °C

Procedure

A mixture of 400 mg (2.0 mmol) 1-methyl-3,5-dinitro-pyridone, 300 mg 1-methyl-piperidin-3-one and 15 ml 2M ammonia in methanol are heated to 60° C. for 20 h. It is concentrated and purified by chromatography (silica gel, CH2Cl2/MeOH 98/2).

Workup

  1. concentrationIt is concentrated
  2. custompurified by chromatography (silica gel, CH2Cl2/MeOH 98/2)

Sources & evidence

ORD record
ord-07c422fa1761439b9f99ca5a9399bf16
Source dataset
uspto-grants-2010_10
Patent number
US07807693B2

Reaction notes

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