1-[4-(3-Phenylpropyl)piperidin-1-yl]octan-3-one → 6-{2-[4-(3-Phenylpropyl)piperidin-1-yl]ethyl}undecan-6-ol

Participants

Reaction Steps

1 equivalent of pentylmagnesium bromide was reacted with 1 equivalent of the compound obtained in Example 2, in anhydrous THF, under nitrogen, at room temperature. The product thus obtained was worked up and purified on a column of silica. The results of the NMR and mass spectrometry analyses were in accordance with the expected structure.

Provenance & Evidence