Water → HCID 86643142, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the product from step 1 (0.30, 1.0 mmol) and intermediate 13 (0.20, 1.0 mmol) and Cs2CO3 (0.65 g, 2.0 mmol) in DMF (5.0 mL) was stirred at 80° C. for 4 h. The reaction mixture was poured into water and extracted with ethyl acetate. The organic phase was washed with water, dried over MgSO4 and concentrated. The residue was purified by chromatography on silica gel to to give the title compound as a solid.

Provenance & Evidence