1H-Indole-3-propanoic acid → HCID 25051881, compound

HRID 1157992Notes

Reaction equation

HRID 1157992 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][CH2:11][C:12]([OH:14])=O)=[CH:2]1.[CH:15]1([N:21]([CH3:25])[CH2:22][CH2:23][NH2:24])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[CH:15]1([N:21]([CH3:25])[CH2:22][CH2:23][NH:24][C:12](=[O:14])[CH2:11][CH2:10][C:3]2[C:4]3[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=3)[NH:1][CH:2]=2)[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 37441H-Indole-3-propanoic acidHCID 7138281N*1*-Cyclohexyl-N*1*-methyl-ethane-1,2-diamine

Product 1

HCID 25051881HCID 25051881, compound

Procedure

Compound 12a was prepared using the amino acid coupling procedure described in Example 10 using 3-(1H-Indol-3-yl)-propionic acid and N1-Cyclohexyl-N1-methyl-ethane-1,2-diamine as the starting materials: LC-MS (Method B, retention time=0.427 min. MS calc'd for C20H30N3O (MH+): 328.2. Found 328.2.

Sources & evidence

ORD record
ord-f79df26a64f947789aa11afa96798b9f
Source dataset
uspto-grants-2010_10
Patent number
US07807704B2

Reaction notes

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