2-Amino-3,3-dimethylbutanoic acid → 5-tert-butyl-2-(cycloheptylamino)-1,3-thiazol-4-one

HRID 1158010Notes

Reaction equation

HRID 1158010 reaction equation
N[CH:2]([C:6]([CH3:9])([CH3:8])[CH3:7])[C:3](O)=[O:4].[CH:10]1([NH:17][C:18]([NH2:20])=[S:19])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1>>[C:6]([CH:2]1[S:19][C:18]([NH:17][CH:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)=[N:20][C:3]1=[O:4])([CH3:9])([CH3:8])[CH3:7]

Participants

3

Reactant 2

HCID 3061312-Amino-3,3-dimethylbutanoic acidHCID 13433274N-Cycloheptylthiourea

Product 1

HCID 1784420245-tert-butyl-2-(cycloheptylamino)-1,3-thiazol-4-one

Procedure

Synthesis was performed from 2-amino-3,3-dimethylbutanoic acid and N-cycloheptylthiourea according to Method E and C.

Workup

  1. customSynthesis

Sources & evidence

ORD record
ord-5f843a625f1d4f949f39ef031650bbc5
Source dataset
uspto-grants-2010_10
Patent number
US07807700B2

Reaction notes

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