Sodium Bicarbonate → HCID 178449047, compound

Participants

Reaction Steps

A mixture of 50% aqueous hypophosphorous acid (6.6 g, 50 mmol) and toluene (30 mL) was cooled in ice and treated with tetrabutyl-ammonium hydroxide solution (32.4 g of 40% solution in water). The pH was adjusted to 7.00 by the addition of sodium bicarbonate. Toluene and the remaining water were removed under reduced pressure. The residue was dissolved in methyl ethyl ketone, filtered, and evaporated. The residue was triturated with diethyl ether and dried to afford a hygroscopic crystalline solid, 15.5 g.

Provenance & Evidence