HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 2-(1-Acetamidocyclohexyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 2-(1-Aminocyclohexyl)acetic acid hydrochloride | HCID 4426693 | — |
| Reactant | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Reactant | 2-(1-Acetamidocyclopentyl)acetic acid | HCID 45119264 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(1-Acetamidocyclohexyl)acetic acid | HCID 25775332 | — |
Reaction Steps
The title compound is prepared analogously as described for (1-acetylamino-cyclopentyl)-acetic acid from (1-amino-cyclohexyl)-acetic acid. MS (LC-MS): [M+H]+=200.1. (HPLC, Waters Symmetry C18 column, 20-95% CH3CN/H2O/3.5 min, 95% CH3CN/H2O, 2 min, CH3CN and H2O containing 0.1% TFA, flow: 0.6 mL/min): 0.81 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807709B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-53345fec2ee04d09af9a562b056b3c03 |
| Source note | uspto-grants-2010_10 |