Pyridine → N1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-methoxyphenyl]-2-phenylacetamide
Reaction equation
[Cl:52][CH2:53][Cl:54].[NH2:1][c:2]1[c:3]([O:23][CH3:24])[cH:4][c:5](-[c:8]2[cH:9][n:10]([CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)[c:11]3[n:12][cH:13][n:14][c:15]([NH2:17])[c:16]23)[cH:6][cH:7]1.[c:31]1([CH2:37][C:38](=[O:39])[Cl:40])[cH:32][cH:33][cH:34][cH:35][cH:36]1.[c:41]1([CH2:42][S:43]([Cl:44])(=[O:45])=[O:46])[cH:47][cH:48][cH:49][cH:50][cH:51]1.[cH:25]1[cH:26][cH:27][n:28][cH:29][cH:30]1>>[NH:1]([c:2]1[c:3]([O:23][CH3:24])[cH:4][c:5](-[c:8]2[cH:9][n:10]([CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)[c:11]3[n:12][cH:13][n:14][c:15]([NH2:17])[c:16]23)[cH:6][cH:7]1)[C:38]([CH2:37][c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1)=[O:39]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-26456df9d19c4351a91e1170156ceb37
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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