HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → Benzyl-cyclopropyl-carbamoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Reactant | N-(cyclohexylmethyl)-N-methylcarbamoyl chloride | HCID 59512492 | — |
| Solvent | Water | HCID 962 | — |
| Product | Benzyl-cyclopropyl-carbamoyl chloride | HCID 10608488 | — |
Reaction Steps
The title compound is prepared analogously as described for cyclohexylmethyl-methylcarbamoyl chloride. TLC, Rf (CH2Cl2/MeOH 95:5)=0.9. MS (LC-MS): [M+H]+=210.2. tR (HPLC, Waters Symmetry C18 column, 20-100% CH3CN/H2O/5 min, CH3CN and H2O containing 0.1% TFA, flow: 0.6 mL/min): 4.67 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807709B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-80a10db795fc43d9b64e324dac4c483e |
| Source note | uspto-grants-2010_10 |