Ethanol → HCID 11700489, compound

Participants

Reaction Steps

The title compound was prepared according to Method B, using 19 (83.4 mg, 0.123 mmol), benzo[b]thiophene-2-boronic acid (109 mg, 0.613 mmol), Pd(PPh)3Cl2 (4.32 mg, 0.00615 mmol), 2 M Na2CO3 (aq., 0.185 mL, 0.369 mmol), EtOH (0.4 mL) and DME (1.6 mL). Purification by RP-LC-MS (35 min gradient of 20-100% CH3CN in 0.05% aqueous formic acid) afforded the product (56.4 mg, 62%) as a white solid.

Provenance & Evidence