Formic Acid → HCID 178457880, compound

Participants

Reaction Steps

In a similar manner as described in example 17, 2-(4-{7-[5-(4-fluorobenzyl)-4H-1,2,4-triazol-3-yl]-8-hydroxy-1,6-naphthyridin-5-yl}piperazin-1-yl)-N-isopropylacetamide (31 mg, 38%) was prepared as the formic acid. 1H NMR (CDCl3): δ 9.13 (d, J=4.0 Hz, 1 H), 8.42 (d, J=8.4 Hz, 1 H), 7.56(dd, J=8.4, 4.0 Hz, 1 H), 7.36 (m, 2 H), 7.02 (m, 2 H), 4.19 (s, 2 H), 4.17-4.13 (m, 1 H), 3.37 (s, 4 H), 3.13 (s, 2 H), 2.82 (s, 4 H), 1.20 (d, J=6.4 Hz, 6 H); MS m/z 505 (M+1).

Provenance & Evidence