HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-(Acetylamino)-9-[(2s)-2-aminopropyl]-9h-pyrido[2,3-b]indole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 2-amino-9-[(2S)-2-aminopropyl]-9H-pyrido[2,3-b]indole-3-carboxamide | HCID 59513644 | — |
| Product | 2-(Acetylamino)-9-[(2s)-2-aminopropyl]-9h-pyrido[2,3-b]indole-3-carboxamide | HCID 24901062 | 63% |
Reaction Steps
xxxi-a (44 mg, 0.104 mmol) was deprotected using the TFA conditions detailed in the preparation of 30 to afford the title compound (66, 29 mg, 63%). NH4OAc standard conditions. DAD
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812018B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-b3f167e899dc448aa4b4c881028f67d2 |
| Source note | uspto-grants-2010_10 |