4-Aminobenzonitrile → HCID 68644193, compound

Participants

Reaction Steps

The reductive amination of 4-(5-formyl-2,4-dimethyl-pyridin-3-yloxymethyl)-benzonitrile (23) (2.3 g, 8.6 mmol) and 4-aminobenzonitrile (4.4 g, 37.2 mmol), as described in Example 21, gave 4-{[5-(4-cyano-benzyloxy)-4,6-dimethyl-pyridin-3-ylmethyl]-amino}-benzonitrile (30) (2.6 g, 82% yield) as a colorless solid.

Provenance & Evidence