HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Chloride → HCID 58636820, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | HCID 58636756 | HCID 58636756 | — |
| Product | HCID 58636820 | HCID 58636820 | 73% |
Reaction Steps
The coupling of 6-[tert-butoxycarbonyl-(3-hydroxy-5-hydroxymethyl-2-methyl-pyridin-4-ylmethyl)-amino]-hexanoic acid (41) (3.0 g, 7.8 mmol) and benzyl chloride (7.0 g, 55 mmol), as described in Example 3, gave 6-[(3-benzyloxy-5-hydroxymethyl-2-methyl-pyridin-4-ylmethyl)-tert-butoxycarbonyl-amino]-hexanoic acid benzyl ester (42) (3.2 g, 73% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812037B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-ca5e500de6c6482e992151d0a94ad41c |
| Source note | uspto-grants-2010_10 |