HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzonitrile → HCID 68644234, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzonitrile | HCID 13396 | — |
| Reactant | HCID 68644138 | HCID 68644138 | — |
| Product | HCID 68644234 | HCID 68644234 | 45.1% |
Reaction Steps
The reductive amination of 4-(5-carboxy-2,4-dimethyl-pyridin-3-yloxy)-benzonitrile (189 mg, 0.75 mmol) and 4-aminobenzonitrile (400 mg, 3.38 mmol), as described in Example 21, gave 4-{[3-(4-cyano-phenoxy)-2,4-dimethyl-pyridin-5-ylmethyl]-amino}-benzonitrile (91) (120 mg, 45% yield) as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812037B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-9d9dc42992154b65b6fb308126525979 |
| Source note | uspto-grants-2010_10 |