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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1158995Generated: November 1, 2026

3-Aminobenzonitrile → HCID 58636869, compound

https://huagongshe.com/reaction/1158995

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AminobenzonitrileHCID 16702—
ReactantHCID 58636735HCID 58636735—
ProductHCID 58636869HCID 5863686924.1%

Reaction Steps

The amide coupling of 3-(3-cyano-benzyloxy)-6-cyclopropyl-2-methyl-isonicotinic acid (189) (128 mg, 0.4 mmol) and 3-aminobenzonitrile (59 mg, 0.4 mol), as described in Example 67, gave 3-(3-cyano-benzyloxy)-N-(3-cyano-phenyl)-6-cyclopropyl-2-methyl-isonicotinamide (192) (39.4 mg, 23% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812037B2
Source datasetuspto-grants-2010_10
ORD IDord-5abacc457fee480eb9b95711185b0f22
Source noteuspto-grants-2010_10