Hydrochloric Acid → HCID 11163457, compound

Participants

Reaction Steps

To N-(t-butoxycarbonyl)-(R)-1,3,4,10b-tetrahydro-9-propyl-7-trifluoromethyl-pyrazino[2,1-a]isoindol-6(2H)-one (25 mg, 0.06 mmol) was added concentrated aqueous hydrogen chloride (1 mL). After 5 min, the solution was concentrated, diluted with water, and lypholized to give the desired product as an off-white solid (19 mg, 89%). %). MS (ESI) 299.3 (M−Cl).

Provenance & Evidence