HCID 68691748, compound → HCID 68688362, compound

Participants

Reaction Steps

To a stirred solution of (R)-2-benzyl-7-methyl-10-methoxy-1,2,3,4,11,11a-hexahydro-pyrazino[1,2-b]isoquinolin-6-one (210 mg, 0.625 mmol) in dry dichloromethane (7 mL), 1M BBr3 in dichloromethane (3.1 mL, 3.1 mmol) was added at −78° C. The reaction was stirred for 2.5 h at RT under Argon. Slowly quenched with MeOH (5 mL) and conc in vacuo to give light brownish residue. MS (ESI) 323 (M+H).

Provenance & Evidence