1-Butanol, 4-bromo-, 1-acetate → 1-(4-Hydroxy-butyl)-1H-indole-3-carboxylic acid thiazol-2-ylamide

HRID 1159137Notes

Reaction equation

HRID 1159137 reaction equation
[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[NH:6][C:7]([C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[NH:11][CH:10]=1)=[O:8].C([O:21][CH2:22][CH2:23][CH2:24][CH2:25]Br)(=O)C>>[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[NH:6][C:7]([C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[N:11]([CH2:25][CH2:24][CH2:23][CH2:22][OH:21])[CH:10]=1)=[O:8]

Participants

3

Reactant 2

HCID 784911-Butanol, 4-bromo-, 1-acetateHCID 17592646N-(1,3-thiazol-2-yl)-1H-indole-3-carboxamide

Product 1

HCID 595139981-(4-Hydroxy-butyl)-1H-indole-3-carboxylic acid thiazol-2-ylamide

Procedure

The title compound was prepared using 1H-indole-3-carboxylic acid thiazol-2-ylamide and 4-bromobutyl acetate as R5X.

Sources & evidence

ORD record
ord-ac185adfd9a94434ac90519dad494e0c
Source dataset
uspto-grants-2010_10
Patent number
US07812043B2

Reaction notes

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