HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → 1-Benzyl-1H-pyrrole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Ethyl 1H-pyrrole-2-carboxylate | HCID 255670 | — |
| Reactant | 1-Benzyl-1H-pyrrole-2-carboxylic acid | HCID 14985839 | — |
| Product | 1-Benzyl-1H-pyrrole-2-carboxylic acid | HCID 14985839 | — |
| Product | HCID 59513988 | HCID 59513988 | — |
Reaction Steps
1-Benzyl-pyrrole-2-carboxylic acid (1.12 g) was prepared from ethyl pyrrole-2-carboxylate (1.39 g, 10.0 mmol) and benzyl bromide (1.26 mL, 11.0 mmol) following general procedures A and B. 1-Benzyl-pyrrole-2-carboxylic acid thiazol-2-ylamide (45 mg) was prepared from 1-benzyl-pyrrole-2-carboxylic acid (50 mg, 0.25 mmol) and 2-aminothiazole (25 mg, 0.25 mmol) following the general procedure F.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812043B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-d32969782fc5418b8d40c5c33819e9c3 |
| Source note | uspto-grants-2010_10 |