4-Fluorophenylboronic acid → HCID 86619565, compound

HRID 1159203Notes

Reaction equation

HRID 1159203 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[N:7][C:8]([Cl:12])=[C:9](Br)[CH:10]=1)=[O:4].[F:13][C:14]1[CH:19]=[CH:18][C:17](B(O)O)=[CH:16][CH:15]=1>>[CH3:1][O:2][C:3](=[O:4])[C:5]1[CH:10]=[C:9]([C:17]2[CH:18]=[CH:19][C:14]([F:13])=[CH:15][CH:16]=2)[C:8]([Cl:12])=[N:7][CH:6]=1

Participants

3

Reactant 2

HCID 2856454-Fluorophenylboronic acidHCID 2764313Methyl 5-bromo-6-chloronicotinate

Product 1

HCID 86619565HCID 86619565, compound

Procedure

The title compound was synthesized in analogy to Example 5a, using 5-bromo-6-chloro-3-pyridinecarboxylic acid methyl ester and 4-fluorophenylboronic acid as starting materials, MS (ISP) 266.1 (M+H)+.

Sources & evidence

ORD record
ord-6760fa8e22974fe5a144cc0be44ed997
Source dataset
uspto-grants-2010_10
Patent number
US07812028B2

Reaction notes

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